Welcome to Endpoint Health

A message from our CEO, Jason Springs

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We believe

Patient Care is
Greater Than
An algorithm  

Endpoint Health is on a mission to bring life-saving targeted therapies to patients with critical illnesses such as sepsis and acute respiratory distress syndrome.

The Challenge

Our sickest patients have few treatment options - they deserve better.

Every year, our children, parents and loved ones develop critical illnesses like sepsis, ARDS and now COVID-19, which affect millions of people, are linked to the majority of hospital deaths, and have costs in the hundreds of billions (USD). Clinical researchers know that these illnesses are not single diseases but rather heterogeneous syndromes, that new therapies are needed, and that each treatment choice should be personalized. But despite the urgent nature of critical illnesses, advances in new and personalized care still lag behind other areas of medicine.

Endpoint Health is on a mission to solve this problem.

Critical illness leads to:


of U.S. Hospital
Mortality 1,2


Annual Cost to
Healthcare System 3


of COVID-19
Mortality 4

1 ICU Outcomes | Philip R. Lee Institute for Health Policy Studies. Philip R. Lee Institute for Health Policy Studies
2 Hall, M. J., Levant, S. & DeFrances, C. J. Trends in inpatient hospital deaths: National Hospital Discharge Survey, 2000-2010. NCHS Data Brief 1–8 (2013).
3 SCCM | Critical Care Statistics. Society of Critical Care Medicine (SCCM)
4 Zhou, F. et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet vol. 395 1054–1062 (2020).
Our Solution

Personalized is Greater Than One-sized

We know that enabling clinicians to successfully care for a critically ill patient means overcoming multiple challenges - complex data analysis, speed clinical decision-making, selection and availability of the right therapies - and most importantly, understanding the specific needs of each patient.

At Endpoint Health we see these challenges as an opportunity to advance the care of patients with critical illnesses as a whole. We are building the world’s first precision medicine ecosystem focused on critical illness and using it to unlock a deeper understanding of patient biology, to see how this biology impacts treatment response, and to develop promising new targeted therapies as well as validate targeted methods of delivering existing care. Our vision is a world where all key therapies needed for each patient are available and personalized to improve outcomes.

Who We Are

“Our goal is not just to create one test or therapy that can be sold for many uses, rather, it is to ensure that every critical therapy needed for each patient is available and personalized in order to accomplish a single goal – improve outcomes.”

Jason Springs
Co-Founder & CEO

Join us in creating something greater.

Find out more about our partnerships and initiatives.